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CTLA4 polyclonal antibody (A01)
Katalog # : H00001493-A01
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50 uL
EUR € 195
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Product Description: Mouse polyclonal antibody raised against a partial recombinant CTLA4.
Immunogen: CTLA4 (NP_005205, 36 a.a. ~ 135 a.a) partial recombinant protein with GST tag.
Sequence: KAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMY
Quality Control Testing: Antibody Reactive Against Recombinant Protein.
Storage Buffer: 50 % glycerol
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Western Blot (Recombinant protein)
Gene Alias: CD152,CELIAC3,CTLA-4,GSE,IDDM12
Gene Description: cytotoxic T-lymphocyte-associated protein 4
Gene Summary: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq
Other Designations: OTTHUMP00000163781,cytotoxic T-lymphocyte-associated antigen 4,cytotoxic T-lymphocyte-associated serine esterase-4,ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
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