Western blot analysis of ASNA1 over-expressed 293 cell line, cotransfected with ASNA1 Validated Chimera RNAi ( Cat # H00000439-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with ASNA1 monoclonal antibody (M03), clone 2H3 (Cat # H00000439-M03 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
ASNA1 is the human homolog of the bacterial arsA gene. In E. coli, ArsA ATPase is the catalytic component of a multisubunit oxyanion pump that is responsible for resistance to arsenicals and antimonials.[supplied by OMIM