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ALOX5 purified MaxPab rabbit polyclonal antibody (D01P)
Katalog # : H00000240-D01P
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100 ug
EUR € 289
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Product Description: Rabbit polyclonal antibody raised against a full-length human ALOX5 protein.
Immunogen: ALOX5 (NP_000689.1, 1 a.a. ~ 674 a.a) full-length human protein.
Sequence: MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI
Quality Control Testing: Antibody reactive against mammalian transfected lysate.
Storage Buffer: In 1x PBS, pH 7.2
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Western Blot (Tissue lysate) ALOX5 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALOX5 expression in human spleen.
Protocol Download
Western Blot (Tissue lysate) ALOX5 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALOX5 expression in mouse spleen.
Protocol Download
Western Blot (Transfected lysate) Western Blot analysis of ALOX5 expression in transfected 293T cell line (H00000240-T02 ) by ALOX5 MaxPab polyclonal antibody.
Protocol Download
Western Blot (Tissue lysate)
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Western Blot (Tissue lysate)
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Western Blot (Transfected lysate)
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Gene Alias: 5-LO,5-LOX,5LPG,LOG5,MGC163204
Gene Description: arachidonate 5-lipoxygenase
Gene Summary: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq
Other Designations: OTTHUMP00000019502,arachidonic acid 5-lipoxygenase,leukotriene A4 synthase
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