Rabbit polyclonal antibody raised against synthetic peptide of MYC.
A synthetic peptide corresponding to residues surrounding amino acids 413 of human MYC-tag.
This antibody detects Myc-Tag proteins overexpressed in cells. It does not detect endogenous levels of the transcription factor c-Myc. It is expected that the Myc-Tag polyclonal antibody will react with proteins/peptides containing Myc-tag from all species.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Western Blot (1-2 ug/mL) Immunoprecipitation (20-40 ug/mL) Immunocytochemistry (10-20 ug/mL) The optimal working dilution should be determined by the end user.
In PBS, pH 7.2 (50% glycerol, 1% BSA, 0.02% thimerosal)
Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq