Rabbit polyclonal antibody raised against synthetic peptide of BCL2.
Immunogen:
A synthetic peptide corresponding to N-terminus of human BCL2.
Host:
Rabbit
Theoretical MW (kDa):
25
Reactivity:
Human, Mouse, Rat
Specificity:
This antibody detects a 25 KDa protein, corresponding to the apparent molecular weight of the alpha isoform of Bcl-2 on SDS-PAGE immunoblots.
Form:
Liquid
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Western Blot (0.5-4 ug/mL) Immunoprecipation (4-8 ug/mL) Immunohistochemistry (10-20 ug/mL) The optimal working dilution should be determined by the end user.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq