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- Home > Products > Polyclonal Ab > Phospho-Specific > RHOA (phospho S188) polyclonal antibody
RHOA (phospho S188) polyclonal antibody
- 目录号 # : PAB7905
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 100 uL
- USD $ 415
- order now, ship in 5 days
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- 该价格仅在China有效。请选择国家。
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Phone : +886-2-87511888
Fax : +886-2-87511166- 产品会直接装运至客户处。
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of RHOA.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S188 of human RHOA.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This peptide sequence is highly conserved in rat and mouse RhoA, but is not found in RhoB or RhoC proteins.
- Form:
- Liquid
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:2000)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Serine phosphorylation negatively regulates RhoA in vivo.
Ellerbroek SM, Wennerberg K, Burridge K.J Biol Chem. 2003 May 23;278(21):19023-31. Epub 2003 Mar 24.
- 2.
- cGMP-dependent protein kinase phosphorylates and inactivates RhoA.
Sawada N, Itoh H, Yamashita J, Doi K, Inoue M, Masatsugu K, Fukunaga Y, Sakaguchi S, Sone M, Yamahara K, Yurugi T, Nakao K.Biochem Biophys Res Commun. 2001 Jan 26;280(3):798-805.
- 3.
- cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha.
Dong JM, Leung T, Manser E, Lim L.J Biol Chem. 1998 Aug 28;273(35):22554-62.
- Application Image
- Western Blot
- ELISA
- Gene Pathway
- Adherens junction
- Axon guidance
- Chemokine signaling pathway
- Colorectal cancer
- Focal adhesion
- Leukocyte transendothelial migration
- Neurotrophin signaling pathway
- Pathogenic Escherichia coli infection - EHEC
- Pathways in cancer
- Regulation of actin cytoskeleton
- T cell receptor signaling pathway
- TGF-beta signaling pathway
- Tight junction
- Vascular smooth muscle contraction
- Wnt signaling pathway
