ADAM33 polyclonal antibody (Cat # PAB6791) (0.3 ug/mL) staining of human prostate lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations:
OTTHUMP00000030126,a disintegrin and metalloprotease 33,a disintegrin and metalloproteinase domain 33,disintegrin and reprolysin metalloproteinase family protein