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- Home > Products > Polyclonal Ab > Human > Transcriptions > ATF2 polyclonal antibody
ATF2 polyclonal antibody
- 目录号 # : PAB6063
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 100 ug
- USD $ 319
- order now, ship in 5 days
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- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of ATF2.
- Immunogen:
- A synthetic peptide corresponding to human ATF2.
- Sequence:
- C-IVMAPSSQSQPSGS
- Host:
- Goat
- Theoretical MW (kDa):
- 54.5
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation.
Monzen K, Hiroi Y, Kudoh S, Akazawa H, Oka T, Takimoto E, Hayashi D, Hosoda T, Kawabata M, Miyazono K, Ishii S, Yazaki Y, Nagai R, Komuro I.J Cell Biol. 2001 May 14;153(4):687-98.
- Entrez GeneID:
- 1386
- Protein Accession#:
- NP_001871.2
- Gene Name:
- ATF2
- Gene Alias:
- CRE-BP1,CREB2,HB16,MGC111558,TREB7
- Gene Description:
- activating transcription factor 2
- Omim ID:
- 123811
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- OTTHUMP00000163262,activating transcription factor 2 splice variant ATF2-var2,cAMP responsive element binding protein 2, formerly
- Gene Pathway
