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- Home > Products > Polyclonal Ab > Human > Apoptosis > PTK2B polyclonal antibody
PTK2B polyclonal antibody
- 目录号 # : PAB5540
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 100 ug
- USD $ 319
- order now, ship in 5 days
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- 该价格仅在China有效。请选择国家。
- 询问我们任何问题
- 付款信息
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Phone : +886-2-87511888
Fax : +886-2-87511166- 产品会直接装运至客户处。
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PTK2B.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding Y402 of human PTK2B.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target cells.
Krishnan HH, Sharma-Walia N, Streblow DN, Naranatt PP, Chandran B.J Virol. 2006 Feb;80(3):1167-80.
- 2.
- Acid sensing in renal epithelial cells.
Gluck SL.J Clin Invest. 2004 Dec;114(12):1696-9.
- 3.
- Nir2, a novel regulator of cell morphogenesis.
Tian D, Litvak V, Toledo-Rodriguez M, Carmon S, Lev S.Mol Cell Biol. 2002 Apr;22(8):2650-62.
- Entrez GeneID:
- 2185
- Gene Name:
- PTK2B
- Gene Alias:
- CADTK,CAKB,FADK2,FAK2,FRNK,PKB,PTK,PYK2,RAFTK
- Gene Description:
- PTK2B protein tyrosine kinase 2 beta
- Omim ID:
- 601212
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CAK beta,OTTHUMP00000128275,OTTHUMP00000162913,calcium-dependent tyrosine kinase,cell adhesion kinase beta,focal adhesion kinase 2,proline-rich tyrosine kinase 2,protein kinase B,protein tyrosine kinase 2 beta,related adhesion focal tyrosine kinase
- Interactome
