Rabbit polyclonal antibody raised against synthetic peptide of ADRB2.
Immunogen:
A synthetic peptide corresponding to residues surrounding S346 of human ADRB2.
Host:
Rabbit
Reactivity:
Human, Mouse
Specificity:
This antibody is specific to ADRB2.
Form:
Liquid
Recommend Usage:
Western Blot (1:500~1:1000) Immunohistochemistry (1:50~1:100) Immunofluorescence (1:500~1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq