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APOE polyclonal antibody
目录号 # : PAB18003
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100 ug
USD $ 319
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Product Description: Rabbit polyclonal antibody raised against recombinant APOE.
Immunogen: Recombinant protein corresponding to human APOE.
Specificity: Recombinant human ApoE4 can be used as a positive control.
Recommend Usage: Western Blot (0.5-4 ug/mL)
Storage Buffer: In PBS pH 7.2 (30% glycerol, 0.5% BSA, 0.01% thimerosal)
Storage Instruction: Store at -20°C. For long term storage store at -80°.
Note: This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Gene Alias: AD2,LPG,MGC1571,apoprotein
Gene Description: apolipoprotein E
Gene Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
Other Designations: apolipoprotein E3
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