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SNAI2 (phospho S155/S158/S160/Y164/Y169) polyclonal antibody
目录号 # : PAB15927
USD $ 415
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Product Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of SNAI2.
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S155/S158/S160/Y164/Y169 of human SNAI2.
Human, Mouse, Rat
Recommend Usage: ELISA (1:2000-1:5000)
Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Storage Buffer: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Storage Instruction: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Note: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Wang SP, Wang WL, Chang YL, Wu CT, Chao YC, Kao SH, Yuan A, Lin CW, Yang SC, Chan WK, Li KC, Hong TM, Yang PC.Nat Cell Biol. 2009 Jun;11(6):694-704. Epub 2009 May 17.
Gene Alias: MGC10182,SLUG,SLUGH1,WS2D
Gene Description: snail homolog 2 (Drosophila)
Gene Summary: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq
Other Designations: OTTHUMP00000195093,neural crest transcription factor SLUG,slug (chicken homolog), zinc finger protein,slug homolog, zinc finger protein,snail 2