Rabbit polyclonal antibody raised against synthetic phosphopeptide of CREB1.
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S133 of human CREB1.
Sequence:
RPSYR
Host:
Rabbit
Theoretical MW (kDa):
40
Reactivity:
Human, Rat
Specificity:
This antibody only recognizes ~40 KDa of human CREB1.
Form:
Liquid
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (1:50) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, pH 7.2 (10% Proclin300)
Storage Instruction:
Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
The tissue lysate derived from rat brain was immunoprecipitated by CREB1 (phospho S133) polyclonal antibody (Cat # PAB12673), then immuno-blotted by the CREB1 (phospho S133) polyclonal antibody (Cat # PAB12617) at 1 : 500 (lane 1), Lane 2 : negative control.
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations:
active transcription factor CREB,cAMP-response element-binding protein-1,transactivator protein