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- Home > Products > Polyclonal Ab > Phospho-Specific > ELK1 (phospho S383) polyclonal antibody
ELK1 (phospho S383) polyclonal antibody
- 目录号 # : PAB0459
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 100 ug
- USD $ 335
- order now, ship in 5 days
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- 该价格仅在China有效。请选择国家。
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ELK1.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S383 of human ELK1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1.
Salinas S, Briancon-Marjollet A, Bossis G, Lopez MA, Piechaczyk M, Jariel-Encontre I, Debant A, Hipskind RA.J Cell Biol. 2004 Jun 21;165(6):767-73.
- 2.
- Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity.
Yang SH, Jaffray E, Hay RT, Sharrocks AD.Mol Cell. 2003 Jul;12(1):63-74.
- 3.
- Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF.
Bebien M, Salinas S, Becamel C, Richard V, Linares L, Hipskind RA.Oncogene. 2003 Mar 27;22(12):1836-47.
- Applications
- Dot Blot (Peptide)
- Dot blot analysis of ELK1 (phospho S383) polyclonal antibody (Cat # PAB0459) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration was 0.5 ug/mL. P-Pab : phospho-antibody; P-Peptide : phospho-peptide; NP-Peptide : non-phospho-peptide.
- Entrez GeneID:
- 2002
- Protein Accession#:
- NP_005220;P19419
- Gene Name:
- ELK1
- Gene Alias:
- -
- Gene Description:
- ELK1, member of ETS oncogene family
- Omim ID:
- 311040
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- ELK1 protein,OTTHUMP00000023224,OTTHUMP00000023225
- Related Disease
