Western blot analysis of EGFR (arrow) in HeLa cell lysates, either induced (Lane 1) or noninduced with EGF (Lane 2). Using EGFR (phospho Y869) polyclonal antibody (Cat # PAB0456) at 1:250 dilution.
Dot Blot (Peptide)
Dot blot analysis of EGFR (phospho Y869) polyclonal antibody (Cat # PAB0456) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration was 0.5 ug/mL. P-Pab : phospho-antibody; P-Peptide : phospho-peptide; NP-Peptide : non-phospho-peptide.
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor