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EGFR (d752-759) (Human) Recombinant Protein
目录号 # : P4818
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100 ug
USD $ 1,239
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Product Description: Human EGFR (NM_005228.3, 672 a.a. - 1210 a.a.) amino acid 752-759 deleted partial protein expressed in Sf9 cells.
Sequence: HIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA
Theoretical MW (kDa): 88.303
Preparation Method:
Insect cell (Sf9) expression system
Purification: GST affinity chromatography
Concentration: 0.151 ug/uL
Activity: 27 pmol/ug x min
Quality Control Testing: 2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer: In 50 mM Hepes, 100 mM NaCl, pH 7.5 (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)
Storage Instruction: Store at -80°C.
Note: Result of activity analysis
Gene Alias: ERBB,ERBB1,HER1,PIG61,mENA
Gene Description: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Gene Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
Other Designations: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor
Adenocarcinoma Adenocarcinoma, Bronchiolo-Alveolar Adenocarcinoma, Mucinous Adenocarcinoma, Papillary Anus Neoplasms Asthma Asthma Astrocytoma Atherosclerosis Barrett Esophagus Bile Duct Neoplasms Biliary Tract Neoplasms Bipolar Disorder Brain Neoplasms Breast cancer Breast Neoplasms Bronchial Hyperreactivity Carcinoma Carcinoma, Adenosquamous
Carcinoma, Giant Cell Carcinoma, Hepatocellular Carcinoma, Large Cell Carcinoma, Non-Small-Cell Lung Carcinoma, Papillary Carcinoma, Renal Cell Carcinoma, Small Cell Carcinoma, Squamous Cell Cardiomyopathy, Dilated Cardiovascular Diseases Cell Transformation, Neoplastic Central Nervous System Neoplasms Cervical Intraepithelial Neoplasia Cholangiocarcinoma Chromosome Aberrations Chromosome Deletion Cleft Lip Cleft Palate Cocarcinogenesis Colon cancer Colonic Neoplasms Colorectal Neoplasms Cystadenocarcinoma, Mucinous Cystadenocarcinoma, Serous Diabetes Mellitus, Type 2 Diarrhea Disease Progression Disease Susceptibility DNA Damage Drug Eruptions Drug Toxicity Edema Endometrial Neoplasms Endometriosis Esophageal Neoplasms Exanthema Genetic Diseases, Inborn Genetic Predisposition to Disease Glioblastoma Glioma Head and Neck Neoplasms Hepatitis C HIV Infections Hyperparathyroidism, Secondary Hypersensitivity Hypopharyngeal Neoplasms Kidney Failure, Chronic Kidney Neoplasms Liver Diseases Liver Neoplasms Lung carcinoma, small cell Lung Neoplasms Lupus Erythematosus, Systemic Lymphatic Metastasis Mental Disorders Mouth Neoplasms Myoma Nasopharyngeal Neoplasms Neoplasm Invasiveness Neoplasm Metastasis Neoplasm Recurrence, Local Neoplasms Neoplasms, Glandular and Epithelial Neoplasms, Radiation-Induced Neoplasms, Second Primary Neoplasms, Squamous Cell Osteosarcoma Otorhinolaryngologic Neoplasms Ovarian cancer Ovarian Neoplasms Pancreatic cancer Pancreatic Neoplasms Papillomavirus Infections Polycystic kidney disease Polycystic Kidney, Autosomal Dominant Precancerous Conditions Prostate cancer Prostatic Hyperplasia Prostatic Neoplasms Pulmonary Disease, Chronic Obstructive Ras oncogene Rectal Neoplasms Recurrence Skin Neoplasms Small Cell Lung Carcinoma Stomach Neoplasms Thyroid Neoplasms Tongue Neoplasms Tonsillar Neoplasms Urinary Bladder Neoplasms Urinary Calculi Uterine Cervical Neoplasms Uterine Neoplasms Viremia Werner syndrome
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