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- Home > Products > Monoclonal Ab > Human > CD Markers > CD28 monoclonal antibody, clone CD28.2 (FITC)
CD28 monoclonal antibody, clone CD28.2 (FITC)
- 目录号 # : MAB6486
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 100 Reactions
- USD $ 319
- order now, ship in 5 days
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Phone : +886-2-87511888
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- Specification
- Product Description:
- Mouse monoclonal antibody raised against CD28.
- Immunogen:
- Native purified CD28 from DC28.1.3.3 hybridoma cells.
- Host:
- Mouse
- Theoretical MW (kDa):
- 44
- Reactivity:
- Human, Non-Human Primates
- Specificity:
- This antibody reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of MW 44 KDa) which is a critical costimulatory receptor of T cells.
- Form:
- Liquid
- Conjugation:
- FITC
- Isotype:
- IgG1
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates.
Jeong SH, Qiao M, Nascimbeni M, Hu Z, Rehermann B, Murthy K, Liang TJ.J Virol. 2004 Jul;78(13):6995-7003.
- 2.
- Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling.
Scharschmidt E, Wegener E, Heissmeyer V, Rao A, Krappmann D.Mol Cell Biol. 2004 May;24(9):3860-73.
- 3.
- Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6.
Marti F, Krause A, Post NH, Lyddane C, Dupont B, Sadelain M, King PD.J Immunol. 2001 Jan 1;166(1):197-206.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 940
- Gene Name:
- CD28
- Gene Alias:
- MGC138290,Tp44
- Gene Description:
- CD28 molecule
- Omim ID:
- 186760
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD28 costimulation is essential for CD4 (MIM 186940)-positive T-cell proliferation, survival, interleukin-2 (IL2; MIM 147680) production, and T-helper type-2 (Th2) development.[supplied by OMIM
- Other Designations:
- CD28 antigen,CD28 antigen (Tp44),T-cell-specific surface glycoprotein
- Related Disease
- Acute Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Behcet Syndrome
- Bronchiolitis, Viral
- Carcinoma, Squamous Cell
- Celiac Disease
- Cholangitis, Sclerosing
- Colon cancer
- Colorectal Neoplasms
- Diabetes Mellitus, Type 1
- Disease Progression
- Drug Eruptions
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hepatitis C
- Hodgkin Disease
- Hypersensitivity, Immediate
