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- Home > Products > Monoclonal Ab > Human > Cytokine > CSF2 monoclonal antibody, clone BVD2-21C11
CSF2 monoclonal antibody, clone BVD2-21C11
- 目录号 # : MAB3288
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 500 ug
- USD $ 335
- order now, ship in 5 days
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- Specification
- Product Description:
- Rat monoclonal antibody raised against recombinant CSF2.
- Immunogen:
- Recombinant protein corresponding to human CSF2.
- Host:
- Rat
- Reactivity:
- Human, Macaque
- Specificity:
- human granulocyte/macrophage colony stimulating factor (GM-CSF) The BVD2-21C11 antibody has been reported to cross react with GM-CSF from Rhesus monkey. This is a neutralizing antibody.
- Form:
- Liquid
- Isotype:
- IgG2a
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Publication Reference
- 1.
- Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE.Immunol Rev. 1992 Jun;127:5-24.
- 2.
- Granulocyte/macrophage colony-stimulating factor and interleukin 3 release from human peripheral blood eosinophils and neutrophils.
Kita H, Ohnishi T, Okubo Y, Weiler D, Abrams JS, Gleich GJ.J Exp Med. 1991 Sep 1;174(3):745-8.
- 3.
- Host-reactive CD4+ and CD8+ T cell clones isolated from a human chimera produce IL-5, IL-2, IFN-gamma and granulocyte/macrophage-colony-stimulating factor but not IL-4.
Bacchetta R, de Waal Malefijt R, Yssel H, Abrams J, de Vries JE, Spits H, Roncarolo MG.J Immunol. 1990 Feb 1;144(3):902-8.
- Application Image
- Immunofluorescence
- Flow Cytometry
- Entrez GeneID:
- 1437
- Gene Name:
- CSF2
- Gene Alias:
- GMCSF,MGC131935,MGC138897
- Gene Description:
- colony stimulating factor 2 (granulocyte-macrophage)
- Omim ID:
- 138960
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq
- Other Designations:
- colony stimulating factor 2,granulocyte-macrophage colony stimulating factor,molgramostin,sargramostim
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Asthma
- Asthma
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- Blindness
- Brain Ischemia
- Bronchial Hyperreactivity
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- Cardiovascular Diseases
- Chlamydia Infections
- Chorioamnionitis
- Coronary Artery Disease
- Coronary Disease
- Dermatitis, Atopic
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- Diabetes Mellitus, Type 2
- Edema
