Rabbit monoclonal antibody raised against synthetic peptide of CD8A.
Immunogen:
A synthetic peptide corresponding to 13 C-terminus amino acids of the cytoplasmic domain of alpha chain of human CD8A.
Host:
Rabbit
Reactivity:
Human
Form:
Liquid
Isotype:
IgG
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Storage Buffer:
In tissue culture supernatant (0.1% sodium azide)
Storage Instruction:
Store at 4°C.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Immunohistochemical staining of CD8A on formalin fixed, paraffin embedded human tonsil. Using CD8A monoclonal antibody, clone SP16 (Cat # MAB2155) at a 1 : 100 dilution.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq