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SRC monoclonal antibody, clone 28
目录号 # : MAB2021
USD $ 515
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Product Description: Mouse monoclonal antibody raised against synthetic peptide of SRC.
Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 519-536 of human SRC.
Human, Mouse, Rat
Quality Control Testing: Antibody Reactive Against Synthetic Peptide.
Recommend Usage: Western blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
Storage Buffer: In PBS, pH 7.2 (1% BSA, 0.1% sodium azide)
Storage Instruction: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Note: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Western Blot (Cell lysate)
Western blot analysis using SRC monoclonal antibody, clone 28 (Cat # MAB2021),on MCF-7 (1), mouse 3T3-L1 (2) and rat PC-12 (3) cell lysates. Antibody used at1 ug/mL .
Gene Alias: ASV,SRC1,c-SRC,p60-Src
Gene Description: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Gene Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations: OTTHUMP00000174476,OTTHUMP00000174477,proto-oncogene tyrosine-protein kinase SRC,protooncogene SRC, Rous sarcoma,tyrosine kinase pp60c-src,tyrosine-protein kinase SRC-1