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- Home > Products > Monoclonal Ab > Human > Binding > Nucleic Acid Binding > DNMT1 monoclonal antibody, clone 60B1220.1
DNMT1 monoclonal antibody, clone 60B1220.1
- 目录号 # : MAB0079
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 100 ug
- USD $ 319
- order now, ship in 5 days
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- 该价格仅在China有效。请选择国家。
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Phone : +886-2-87511888
Fax : +886-2-87511166- 产品会直接装运至客户处。
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of DNMT1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 637-650 of human DNMT1.
- Sequence:
- EKDDREDKENAFKR
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Zebra fish
- Form:
- Liquid
- Isotype:
- IgG1
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.05% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Arsenic Induces Functional Re-Expression of Estrogen Receptor ? by Demethylation of DNA in Estrogen Receptor-Negative Human Breast Cancer.
Du J, Zhou N, Liu H, Jiang F, Wang Y, Hu C, Qi H, Zhong C, Wang X, Li Z.PLoS One. 2012;7(4):e35957. Epub 2012 Apr 27.
- 2.
- Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.
Cheng JC, Auersperg N, Leung PC.Oncogene. 2011 Apr 11. [Epub ahead of print]
- 3.
- CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.
Guastafierro T, Cecchinelli B, Zampieri M, Reale A, Riggio G, Sthandier O, Zupi G, Calabrese L, Caiafa P.J Biol Chem. 2008 Aug 8;283(32):21873-80. Epub 2008 Jun 5.
- 4.
- Helicobacter pylori regulates p21(WAF1) by histone H4 acetylation.
Xia G, Schneider-Stock R, Diestel A, Habold C, Krueger S, Roessner A, Naumann M, Lendeckel U.Biochem Biophys Res Commun. 2008 May 2;369(2):526-31. Epub 2008 Feb 25.
- 5.
- Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells.
Ji W, Yang L, Yu L, Yuan J, Hu D, Zhang W, Yang J, Pang Y, Li W, Lu J, Fu J, Chen J, Lin Z, Chen W, Zhuang Z.Carcinogenesis. 2008 Jun;29(6):1267-75. Epub 2008 Jan 19.
- 6.
- Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin.
Mabaera R, Greene MR, Richardson CA, Conine SJ, Kozul CD, Lowrey CH.Blood. 2008 Jan 1;111(1):411-20. Epub 2007 Oct 4.
- 7.
- Role of the polycomb repressive complex 2 in acute promyelocytic leukemia.
Villa R, Pasini D, Gutierrez A, Morey L, Occhionorelli M, Vire E, Nomdedeu JF, Jenuwein T, Pelicci PG, Minucci S, Fuks F, Helin K, Di Croce L.Cancer Cell. 2007 Jun;11(6):513-25.
- Entrez GeneID:
- 1786
- Protein Accession#:
- NP_001370
- Gene Name:
- DNMT1
- Gene Alias:
- AIM,CXXC9,DNMT,FLJ16293,MCMT,MGC104992
- Gene Description:
- DNA (cytosine-5-)-methyltransferase 1
- Omim ID:
- 126375
- Gene Ontology:
- Hyperlink
- Gene Summary:
- DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CXXC finger protein 9,DNA methyltransferase 1
- Gene Pathway
- Related Disease
