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TLR2 monoclonal antibody, clone 1030A5.138
目录号 # : MAB0066
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200 uL
USD $ 319
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Product Description: Mouse monoclonal antibody raised against full length recombinant TLR2.
Immunogen: Recombinant protein corresponding to extracellular region of human TLR2.
Recommend Usage: The optimal working dilution should be determined by the end user.
Storage Buffer: In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction: Store at 4°C. For long term storage store at -20°C.
Note: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
4.
Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk.
5.
Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase.
Western Blot (Cell lysate) Western blot analysis of TLR2 in 30 ugs of Ramos whole cell lysate. Using TLR2 monoclonal antibody, clone 1030A5.138 (Cat # MAB0066) at 1 : 500.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) IHC analysis of TLR2 in paraffin-embedded human spleen tissue. Using TLR2 monoclonal antibody, clone 1030A5.138 (Cat # MAB0066) at 1 : 100 (left) and isotype control (right) .
Flow Cytometry Intracellular flow analysis of TLR2 in 106 THP-1 cells. Using 5 uL of TLR2 monoclonal antibody, clone 1030A5.138 (Cat # MAB0066). The shaded histogram represents ThP-1 cells with no antibody present; Green represents isotype control ; red represents TLR2 antibody.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Description: toll-like receptor 2
Gene Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
Other Designations: toll/interleukin 1 receptor-like 4
Acute Disease Aggressive Periodontitis Agricultural Workers' Diseases Amyloidosis Arthritis, Reactive Arthritis, Rheumatoid Aspergillosis Aspergillosis, Allergic Bronchopulmonary Asthma Asthma Atherosclerosis Atherosclerosis Bacteremia Bacterial Infections Bacteriuria Behcet Syndrome Birth Weight Breast Neoplasms Bronchial Hyperreactivity
Bronchiectasis Bronchiolitis Obliterans Bronchiolitis, Viral Calcinosis Candidiasis Candidiasis, Oral Cardiovascular Diseases Carotid Artery Diseases Chagas Cardiomyopathy Chlamydia Infections Chorioamnionitis Chronic Disease Chronic Periodontitis Colitis, Ulcerative Colorectal Neoplasms Communicable Diseases Connective Tissue Diseases Coronary Artery Disease Coronary Disease Coronary Restenosis Critical Illness Crohn Disease Crohn's disease Cystitis Cytomegalovirus Infections Dental Plaque Dermatitis, Atopic Diabetes Complications Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Disease Progression Disease Susceptibility Duodenal Ulcer Eczema Edema Elephantiasis, Filarial Epidermal Necrolysis, Toxic Familial Mediterranean Fever Familial Mediterranean fever Fetal Diseases Fetal Membranes, Premature Rupture Filariasis Food Hypersensitivity Gallbladder Neoplasms Gastritis Genetic Predisposition to Disease Genital Diseases, Female Gingival Hemorrhage Glioblastoma Glioma Glomerulonephritis, IGA Gram-Negative Bacterial Infections Head and Neck Neoplasms Helicobacter Infections Hematologic Diseases Hematologic Neoplasms Hepatitis C, Chronic Herpes Genitalis HIV Infections Hodgkin Disease Hypersensitivity Hypersensitivity, Immediate Infant, Premature, Diseases Infection Inflammation Inflammatory Bowel Diseases Insulin Resistance Leishmaniasis, Cutaneous Leprosy Leprosy, Lepromatous Leukemia Leukemia, Myeloid Leukemia, Myeloid, Acute Low Tension Glaucoma Lung Diseases Lung Diseases, Fungal Lung Neoplasms Lupus Erythematosus, Systemic Lyme Disease Lymphoma Lymphoma, Non-Hodgkin Lymphoproliferative Disorders Malaria Malaria, Cerebral Malaria, Falciparum Meningeal Neoplasms Meningioma Meningitis, Meningococcal Meningococcal Infections Metaplasia Multiple Myeloma Multiple Sclerosis, Relapsing-Remitting Musculoskeletal Diseases Mycobacterium avium-intracellulare Infection Mycobacterium Infections, Atypical Mycoses Myocardial Infarction Nasal Polyps Neoplasm Recurrence, Local Neoplasms, Second Primary Nephritis Obesity Obesity Obstetric Labor, Premature Occupational Diseases Otitis Media Pancreatitis, Acute Necrotizing Papillomavirus Infections Parasitemia Peptic Ulcer Periodontal Diseases Periodontitis Pneumococcal Infections Pneumonia Pneumonia, Pneumococcal Pre-Eclampsia Pregnancy Complications, Hematologic Pregnancy Complications, Infectious Premature Birth Prostate cancer Prostatic Neoplasms Puerperal Disorders Pulmonary Disease, Chronic Obstructive Purpura, Schoenlein-Henoch Purpura, Thrombocytopenic, Idiopathic Pyelonephritis Q Fever Recurrence Respiratory Sounds Respiratory Syncytial Virus Infections Respiratory Tract Infections Rheumatic Fever Rheumatic Heart Disease Rhinitis Rhinitis, Allergic, Perennial Rhinitis, Allergic, Seasonal Salmonella Infections Sarcoidosis Sarcoidosis, Pulmonary Sepsis Shock, Septic Sinusitis Skin Diseases Spondylitis, Ankylosing Staphylococcal Infections Staphylococcal Skin Infections Stevens-Johnson Syndrome Stomach Neoplasms Streptococcal Infections Systemic Inflammatory Response Syndrome Tobacco Use Disorder Tuberculosis Tuberculosis, Lymph Node Tuberculosis, Meningeal Tuberculosis, Pleural Tuberculosis, Pulmonary Urinary Bladder Neoplasms Urinary Tract Infections Uterine Cervical Neoplasms Vaginosis, Bacterial Virus Diseases Waldenstrom Macroglobulinemia Werner syndrome
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