TNFRSF1B (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human TNFRSF1B.
Calibration Range:
7.8 to 500 pg/mL
Limit of Detection:
2 pg/mL
Reactivity:
Human
Quality Control Testing:
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction:
Store the kit at 4°C for 4 months. For long term storage, please store at -20°C for 8 months.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq