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- Home > Products > Polyclonal Ab > Human > Binding > Nucleic Acid Binding > LASS6 polyclonal antibody (A01)
LASS6 polyclonal antibody (A01)
- 目录号 # : H00253782-A01
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 50 uL
- USD $ 229
- order now, ship next day
-
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- 该价格仅在China有效。请选择国家。
- 询问我们任何问题
- 付款信息
信用卡 :
Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166- 产品会直接装运至客户处。
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant LASS6.
- Immunogen:
- LASS6 (NP_982288, 62 a.a. ~ 131 a.a) partial recombinant protein with GST tag.
- Sequence:
- PCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTR
- Host:
- Mouse
- Reactivity:
- Human
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.81 KDa) .
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Publication Reference
- 1.
- siRNA-Mediated Down-regulation of Ceramide Synthase 1 Leads to Apoptotic Resistance in Human Head and Neck Squamous Carcinoma Cells after Photodynamic Therapy.
Separovic D, Breen P, Joseph N, Bielawski J, Pierce JS, VAN Buren E, Gudz TI.Anticancer Res. 2012 Jul;32(7):2479-85.
- 2.
- Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.
Separovic D, Breen P, Joseph N, Bielawski J, Pierce JS, VAN Buren E, Gudz TI.Anticancer Res. 2012 Mar;32(3):753-60.
- 3.
- Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+ and ER/Golgi Membrane Network.
Senkal CE, Ponnusamy S, Manevich Y, Meyers-Needham M, Saddoughi SA, Mukhopadyay A, Dent P, Bielawski J, Ogretmen B.J Biol Chem. 2011 Dec 9;286(49):42446-58. Epub 2011 Oct 19.
- 4.
- Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.
Senkal CE, Ponnusamy S, Bielawski J, Hannun YA, Ogretmen B.FASEB J. 2009 Sep 1. [Epub ahead of print]
- 5.
- Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.
White-Gilbertson S, Mullen T, Senkal C, Lu P, Ogretmen B, Obeid L, Voelkel-Johnson C.Oncogene. 2009 Feb 26;28(8):1132-41. Epub 2009 Jan 12.
- 6.
- JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction.
Yu J, Novgorodov SA, Chudakova D, Zhu H, Bielawska A, Bielawski J, Obeid LM, Kindy MS, Gudz TI.J Biol Chem. 2007 Aug 31;282(35):25940-9. Epub 2007 Jul 3.
- 7.
- Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas.
Senkal CE, Ponnusamy S, Rossi MJ, Bialewski J, Sinha D, Jiang JC, Jazwinski SM, Hannun YA, Ogretmen B.Mol Cancer Ther. 2007 Feb;6(2):712-22.
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Related Disease
