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- Home > Products > siRNA/Chimera > Pre-design Chimera > Others > KLK5 Pre-design Chimera RNAi
KLK5 Pre-design Chimera RNAi
- 目录号 # : H00025818-R02
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 10 nmol
- USD $ 239
- order now, ship in 2 weeks
-
- 20 nmol
- USD $ 289
- order now, ship in 2 weeks
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- 该价格仅在China有效。请选择国家。
- 询问我们任何问题
- 付款信息
信用卡 :
Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166- 产品会直接装运至客户处。
- Specification
- Product Description:
- Homo sapiens kallikrein-related peptidase 5 (KLK5), transcript variant 2, mRNA
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_001077491
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 25818
- Gene Name:
- KLK5
- Gene Alias:
- KLK-L2,KLKL2,SCTE
- Gene Description:
- kallikrein-related peptidase 5
- Omim ID:
- 605643
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
- Other Designations:
- kallikrein 5,kallikrein-like protein 2,stratum corneum tryptic enzyme
- Related Disease
