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- Home > Products > Polyclonal Ab > Human > Cell Cycle > TARDBP polyclonal antibody (A01)
TARDBP polyclonal antibody (A01)
- 目录号 # : H00023435-A01
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 50 uL
- USD $ 229
- order now, ship next day
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- 该价格仅在China有效。请选择国家。
- 询问我们任何问题
- 付款信息
信用卡 :
Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166- 产品会直接装运至客户处。
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length recombinant TARDBP.
- Immunogen:
- TARDBP (AAH01487.1, 1 a.a. ~ 260 a.a) full-length recombinant protein with GST tag.
- Sequence:
- MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNA
- Host:
- Mouse
- Reactivity:
- Human
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (54.34 KDa) .
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Publication Reference
- 1.
- Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS.
Ayala V, Granado-Serrano AB, Cacabelos D, Naudi A, Ilieva EV, Boada J, Caraballo-Miralles V, Llado J, Ferrer I, Pamplona R, Portero-Otin M.Acta Neuropathol. 2011 Jun 25. [Epub ahead of print]
- 2.
- Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression.
Tatom JB, Wang DB, Dayton RD, Skalli O, Hutton ML, Dickson DW, Klein RL.Mol Ther. 2009 Apr;17(4):607-13. Epub 2009 Feb 17.
- 3.
- TDP-43 pathology in familial British dementia.
Schwab C, Arai T, Hasegawa M, Akiyama H, Yu S, McGeer PL.Acta Neuropathol. 2009 Aug;118(2):303-11. Epub 2009 Mar 13.
- 4.
- Colocalization of Transactivation-Responsive DNA-Binding Protein 43 and Huntingtin in Inclusions of Huntington Disease.
Schwab C, Arai T, Hasegawa M, Yu S, McGeer PL.J Neuropathol Exp Neurol. 2008 Dec;67(12):1159-65.
- 5.
- A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity.
Johnson BS, McCaffery JM, Lindquist S, Gitler AD.Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6439-44. Epub 2008 Apr 23.
- Applications
- Western Blot (Cell lysate)
- TARDBP polyclonal antibody (A01), Lot # Abnova060510QCS1 Western Blot analysis of TARDBP expression in IMR-32 ( Cat # L008V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 23435
- GeneBank Accession#:
- BC001487
- Protein Accession#:
- AAH01487.1
- Gene Name:
- TARDBP
- Gene Alias:
- ALS10,TDP-43
- Gene Description:
- TAR DNA binding protein
- Omim ID:
- 605078
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq
- Other Designations:
- OTTHUMP00000002171,TAR DNA-binding protein-43
