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GADD45G monoclonal antibody (M01), clone 1D3
目录号 # : H00010912-M01
访问频率 :
50 ug
USD $ 319
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Product Description:
Mouse monoclonal antibody raised against a full length recombinant GADD45G.
Immunogen:
GADD45G (AAH19325, 1 a.a. ~ 159 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence:
MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFCVLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCILISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE
Quality Control Testing:
Antibody Reactive Against Recombinant Protein. Western Blot detection against Immunogen (43.23 KDa) .
Storage Buffer:
In 1x PBS, pH 7.2
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
1.
The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. Scuto A, Kirschbaum M, Kowolik C, Kretzner L, Juhasz A, Atadja P, Pullarkat V, Bhatia R, Forman S, Yen Y, Jove R.Blood. 2008 May 15;111(10):5093-100. Epub 2008 Mar 18.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GADD45G is approximately 0.03ng/ml as a capture antibody.
Protocol Download
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
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Gene Alias:
CR6,DDIT2,GADD45gamma,GRP17
Gene Description:
growth arrest and DNA-damage-inducible, gamma
Gene Summary:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq
Other Designations:
GADD45-gamma,OTTHUMP00000021623,gadd-related protein, 17 kD