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PPP2R2B monoclonal antibody (M23), clone 1B10   

  • 目录号 # : H00005521-M23
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  • 购物车
  • 100 ug
  • USD $ 319
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a full-length recombinant PPP2R2B.
  • Immunogen:
  • PPP2R2B (AAH31790, 1 a.a. ~ 443 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • MEEDIDTRKINNSFLRDHSYATEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFSKKILHTAWHPSENIIAVAATNNLYIFQDKVN
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2b Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Storage Buffer:
  • In 1x PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of PPP2R2B transfected lysate using anti-PPP2R2B monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PPP2R2B MaxPab rabbit polyclonal antibody.
  • Protocol Download
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5521
  • Gene Name:
  • PPP2R2B
  • Gene Alias:
  • B55-BETA,FLJ95686,MGC24888,PP2A-B55BETA,PP2A-PR55B,PP2AB-BETA,PP2APR55-BETA,PR2AB-BETA,PR2AB55-BETA,PR2APR55-BETA,PR52B,PR55-BETA,SCA12
  • Gene Description:
  • protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform
  • Gene Summary:
  • The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12. [provided by RefSeq
  • Other Designations:
  • PP2A, subunit B, B-beta isoform,PP2A, subunit B, R2-beta isoform,beta isoform of regulatory subunit B55, protein phosphatase 2,protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform,serine/threonine protein phosphatase 2A, 55 kDa
  • Gene Pathway
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