This antibody pair set comes with matched antibody pair to detect and quantify protein level of human HLA-DPA1.
Reactivity:
Human
Quality Control Testing:
Standard curve using recombinant protein ( H00003113-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
Supplied Product:
Antibody pair set content: 1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-HLA-DPA1 (100 ug) 2. Detection antibody: mouse purified polyclonal anti-HLA-DPA1 (20 ug) *Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
Storage Instruction:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq
Other Designations:
HLA class II histocompatibility antigen, DP alpha chain,MHC class II HLA-DPA1 antigen,MHC class II antigen,OTTHUMP00000029066,OTTHUMP00000062983
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