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- Home > Products > siRNA/Chimera > Pre-design Chimera > Membrane > Receptor > HFE Pre-design Chimera RNAi
HFE Pre-design Chimera RNAi
- 目录号 # : H00003077-R06
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 10 nmol
- USD $ 239
- order now, ship in 2 weeks
-
- 20 nmol
- USD $ 289
- order now, ship in 2 weeks
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- 该价格仅在China有效。请选择国家。
- 询问我们任何问题
- 付款信息
信用卡 :
Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166- 产品会直接装运至客户处。
- Specification
- Product Description:
- Homo sapiens hemochromatosis (HFE), transcript variant 6, mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_139006
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 3077
- Gene Name:
- HFE
- Gene Alias:
- HFE1,HH,HLA-H,MGC103790,dJ221C16.10.1
- Gene Description:
- hemochromatosis
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq
- Other Designations:
- MHC class I-like protein HFE,hemochromatosis protein,hereditary hemochromatosis protein HLA-H
- Related Disease
- Abortion, Spontaneous
- Activated Protein C Resistance
- Acute Disease
- Adenocarcinoma
- Adenoma
- Adenomatous Polyps
- Albuminuria
- Alcoholism
- alpha 1-Antitrypsin Deficiency
- alpha-Thalassemia
- Alzheimer Disease
- Alzheimer disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Anemia
- Anemia, Iron-Deficiency
- Anemia, Sickle Cell
- Anemia, sickle cell
- Arteriosclerosis
