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HFE polyclonal antibody (A01)
目录号 # : H00003077-A01
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50 uL
USD $ 229
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Product Description: Mouse polyclonal antibody raised against a partial recombinant HFE.
Immunogen: HFE (NP_000401, 115 a.a. ~ 205 a.a) partial recombinant protein with GST tag.
Sequence: SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQ
Quality Control Testing: Antibody Reactive Against Recombinant Protein.
Storage Buffer: 50 % glycerol
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Gene Alias: HFE1,HH,HLA-H,MGC103790,dJ221C16.10.1
Gene Description: hemochromatosis
Gene Summary: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq
Other Designations: MHC class I-like protein HFE,hemochromatosis protein,hereditary hemochromatosis protein HLA-H
Abortion, Spontaneous Activated Protein C Resistance Acute Disease Adenocarcinoma Adenoma Adenomatous Polyps Albuminuria Alcoholism alpha 1-Antitrypsin Deficiency alpha-Thalassemia Alzheimer Disease Alzheimer disease Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis Anemia Anemia, Iron-Deficiency Anemia, Sickle Cell Anemia, sickle cell Arteriosclerosis
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