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CFH purified MaxPab mouse polyclonal antibody (B01P)
目录号 # : H00003075-B01P
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50 ug
USD $ 319
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Product Description: Mouse polyclonal antibody raised against a full-length human CFH protein.
Immunogen: CFH (NP_001014975.1, 1 a.a. ~ 449 a.a) full-length human protein.
Sequence: MRLLAKIICLMLWAICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPTPRCIRVSFTL
Quality Control Testing: Antibody reactive against mammalian transfected lysate.
Storage Buffer: In 1x PBS, pH 7.2
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Western Blot (Transfected lysate) Western Blot analysis of CFH expression in transfected 293T cell line (H00003075-T01 ) by CFH MaxPab polyclonal antibody.
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Western Blot (Transfected lysate)
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Gene Alias: ARMD4,ARMS1,CFHL3,FH,FHL1,HF,HF1,HF2,HUS,MGC88246
Gene Description: complement factor H
Gene Summary: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations: H factor 1 (complement),H factor 2 (complement),OTTHUMP00000033598,age-related maculopathy susceptibility 1,beta-1-H-globulin,beta-1H,complement factor H, isoform b,factor H,factor H-like 1
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Choroidal Neovascularization Choroiditis Coronary Artery Disease Coronary Disease Crohn's disease Diabetes Complications Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetic Nephropathies Diabetic Retinopathy Disease Progression Disease Susceptibility Diseases in Twins Ductus Arteriosus, Patent Edema Functional Laterality Genetic Predisposition to Disease Geographic Atrophy Glomerulonephritis, IGA Glomerulonephritis, Membranoproliferative Hemolytic-Uremic Syndrome Hyperlipoproteinemia Type II Hypertension Immune System Diseases Infant, Premature, Diseases Inflammation Inflammatory Bowel Diseases Kidney Failure, Chronic Lung Neoplasms Lymphoma, Non-Hodgkin Macular Degeneration Meningococcal Infections Myocardial Infarction Nephritis, Hereditary Obesity Obesity Peripheral Vascular Diseases Pre-Eclampsia Prostate cancer Prostatic Neoplasms Pseudoxanthoma Elasticum Pulmonary Disease, Chronic Obstructive Purpura, Thrombotic Thrombocytopenic Recurrence Retinal Degeneration Retinal Diseases Retinal Drusen Retinal Neovascularization Retinopathy of Prematurity Spinocerebellar ataxia Staphylococcal Infections Stroke Systemic Inflammatory Response Syndrome Taste Urinary Bladder Neoplasms Venous Thrombosis Werner syndrome Wet Macular Degeneration
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