Immunoprecipitation of FXN transfected lysate using anti-FXN MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with FXN purified MaxPab mouse polyclonal antibody (B01P) (H00002395-B01P).
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq