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- Home > Products > Proteins/Peptides > Human > Partial-length > Enzyme > DUSP5 (Human) Recombinant Protein (Q01)
DUSP5 (Human) Recombinant Protein (Q01)
- 目录号 # : H00001847-Q01
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 10 ug
- USD $ 319
- order now, ship next day
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- 25 ug
- USD $ 485
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- Specification
- Product Description:
- Human DUSP5 partial ORF ( NP_004410, 286 a.a. - 384 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- LKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC
- Theoretical MW (kDa):
- 36.63
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 1847
- GeneBank Accession#:
- NM_004419
- Protein Accession#:
- NP_004410
- Gene Name:
- DUSP5
- Gene Alias:
- DUSP,HVH3
- Gene Description:
- dual specificity phosphatase 5
- Omim ID:
- 603069
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq
- Other Designations:
- OTTHUMP00000020476,VH1-like phosphatase 3,serine/threonine specific protein phosphatase
- Gene Pathway
