Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq
Other Designations:
OTTHUMP00000029131,OTTHUMP00000029133,OTTHUMP00000029137,OTTHUMP00000174486,RNCC protein,chloride channel ABP,nuclear chloride ion channel protein,p64CLCP