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BRAF monoclonal antibody (M02), clone 3D2
目录号 # : H00000673-M02
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100 ug
USD $ 319
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Product Description: Mouse monoclonal antibody raised against a partial recombinant BRAF.
Immunogen: BRAF (NP_004324, 346 a.a. ~ 445 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence: FRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRD
Quality Control Testing: Antibody Reactive Against Recombinant Protein.
Storage Buffer: In 1x PBS, pH 7.2
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
1.
An analysis of protein-protein interactions in cross-talk pathways reveals CRKL as a novel prognostic marker in hepatocellular carcinoma.
Western Blot (Tissue lysate) BRAF monoclonal antibody (M02), clone 3D2. Western Blot analysis of BRAF expression in human pancreas.
Protocol Download
Sandwich ELISA (Recombinant protein) Detection limit for recombinant GST tagged BRAF is approximately 0.03ng/ml as a capture antibody.
Protocol Download
In situ Proximity Ligation Assay (Cell)Proximity Ligation Analysis of protein-protein interactions between MAPK3 and BRAF. HeLa cells were stained with anti-MAPK3 rabbit purified polyclonal 1:1200 and anti-BRAF mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
Western Blot (Tissue lysate)
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Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
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In situ Proximity Ligation Assay (Cell)enlarge
Gene Alias: B-RAF1,BRAF1,FLJ95109,MGC126806,MGC138284,RAFB1
Gene Description: v-raf murine sarcoma viral oncogene homolog B1
Gene Summary: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq
Other Designations: 94 kDa B-raf protein,B-Raf proto-oncogene serine/threonine-protein kinase (p94),Murine sarcoma viral (v-raf) oncogene homolog B1
Abnormalities, Multiple Adenocarcinoma Adenocarcinoma, Follicular Adenocarcinoma, Mucinous Adenocarcinoma, Papillary Adenoma Adenoma, Oxyphilic Adrenal Cortex Neoplasms Alcoholism Articulation Disorders Astrocytoma Brain Neoplasms Breast cancer Breast Neoplasms Carcinoma Carcinoma, Basal Cell Carcinoma, Medullary Carcinoma, Non-Small-Cell Lung Carcinoma, Papillary
Carcinoma, Papillary, Follicular Carcinoma, Squamous Cell Carcinoma, Transitional Cell Cell Transformation, Neoplastic Chromosomal Instability Chromosome Aberrations Cognition Cognition Disorders Colon cancer Colonic Neoplasms Colonic Polyps Colorectal Neoplasms Colorectal Neoplasms, Hereditary Nonpolyposis Common Bile Duct Neoplasms Craniofacial Abnormalities Cystadenocarcinoma, Mucinous Cystadenocarcinoma, Serous Cystadenoma, Serous Developmental Disabilities Dilatation, Pathologic Disease Progression Diseases in Twins Dyslexia, Acquired Ectodermal Dysplasia Endometrial Hyperplasia Endometrial Neoplasms Endometriosis Eosinophilia Esophageal Neoplasms Gastrointestinal Stromal Tumors Genetic Predisposition to Disease Glioma Goiter Goiter, Nodular Hashimoto Disease Head and Neck Neoplasms Hearing Heart Defects, Congenital Hyperpigmentation Hyperplasia Immunologic Deficiency Syndromes Language Disorders Liver Neoplasms Lung Neoplasms Lymphatic Metastasis Lymphoma, Non-Hodgkin Malignant melanoma Melanoma Memory Microsatellite Instability Motor Skills Nasopharyngeal Neoplasms Necrosis Neoplasm Invasiveness Neoplasm Metastasis Neoplasm Recurrence, Local Neoplasms Neoplasms, Germ Cell and Embryonal Neoplasms, Glandular and Epithelial Neoplasms, Multiple Primary Neoplasms, Radiation-Induced Nerve Sheath Neoplasms Neurofibromatosis Neurofibromatosis 1 Nevus Nevus, Pigmented Noonan Syndrome Obesity Ovarian cancer Ovarian Neoplasms Pancreatic cancer Pancreatic Neoplasms Papillomavirus Infections Precancerous Conditions Prostatic Neoplasms Ras oncogene Rectal Neoplasms Recurrence Salivary Gland Neoplasms Skin Neoplasms Stomach Neoplasms Syndrome Testicular Neoplasms Thyroid Diseases Thyroid Neoplasms Thyroid Nodule Thyroiditis, Autoimmune Tobacco Use Disorder Urinary Bladder Neoplasms
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