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- Home > Products > siRNA/Chimera > Pre-design Chimera > Others > ABO Pre-design Chimera RNAi
ABO Pre-design Chimera RNAi
- 目录号 # : H00000028-R01
- 访问频率 :
- 尺寸
- 价格
- 库存
- 可得性
- 购物车
- 10 nmol
- USD $ 239
- order now, ship in 2 weeks
-
- 20 nmol
- USD $ 289
- order now, ship in 2 weeks
-
-
- 该价格仅在China有效。请选择国家。
- 询问我们任何问题
- 付款信息
信用卡 :
Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166- 产品会直接装运至客户处。
- Specification
- Product Description:
- Homo sapiens ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) (ABO), mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_020469
- Target Region:
- Coding sequence
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 28
- Gene Name:
- ABO
- Gene Alias:
- A3GALNT,A3GALT1,GTB,NAGAT
- Gene Description:
- ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
- Omim ID:
- 110300
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq
- Other Designations:
- ABO glycocyltransferase,ABO glycosyltransferase,B(A) alpha-1,3-galactosyltransferase,alpha 1-3-N-acetylgalactosaminyltransferase,histo-blood group A2 transferase,histo-blood group ABO protein
- Related Disease
- Activated Protein C Resistance
- AIDS-Related Opportunistic Infections
- alpha-Thalassemia
- Alzheimer disease
- Anemia, sickle cell
- Asthma
- Asthma
- Atherosclerosis
- Attention Deficit Disorder with Hyperactivity
- Birth Weight
- Blood Group Incompatibility
- Brain Ischemia
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Cardiovascular Diseases
- Coronary Artery Disease
- Cystic Fibrosis
- Cystic fibrosis
- Diabetes Mellitus, Type 1
