Rabbit polyclonal antibody raised against synthetic peptide of BID.
Immunogen:
A synthetic peptide corresponding to residues surrounding amino acids 37 of human BID.
Host:
Rabbit
Reactivity:
Human
Form:
Liquid
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Western Blot (0.5-4 ug/mL) Immunoprecipitation (5-10 ug/mL) Immunohistochemistry (20-40 ug/mL) The optimal working dilution should be determined by the end user.
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq
Other Designations:
BH3-interacting domain death agonist,BID isoform ES(1b),BID isoform L(2),BID isoform Si6,Human BID coding sequence,OTTHUMP00000196197,apoptic death agonist,desmocollin type 4