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IL1B monoclonal antibody, clone Interleukin-1
目录号 # : MAB7383
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500 ug
USD $ 619
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Product Description: Mouse monoclonal antibody raised against recombinant IL1B.
Immunogen: Recombinant protein corresponding to human IL1B.
Recommend Usage: Blocking (4-8 ug/mL)
Storage Buffer: Lyophilized from PBS.
Storage Instruction: Store at -20°C on dry atmosphere.
Gene Alias: IL-1,IL1-BETA,IL1F2
Gene Description: interleukin 1, beta
Gene Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
Other Designations: catabolin,preinterleukin 1 beta,pro-interleukin-1-beta
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