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AbVideo™ - Cell Biology

  • The Ciliopathy-associated Protein Homologs RPGRIP1

    The aim of this study was to gain more insight in the function of two ciliopathy-associated protein homologs, RPGR interacting protein 1 (RPGRIP1), and RPGRIP1-like protein (RPGRIP1L). Base on the data, the authors hypothesize that RPGRIP1 and RPGRIP1L function as cilium-specific scaffolds that recruit a Nek4 signaling network which regulates cilium stability.

    Publish: 2011/8/30

  • BAD in Cancer Signalling

    BAD (Bcl-2 antagonist of cell death) belongs to the pro-apoptotic BH3-only subfamily of Bcl- 2 proteins. Physiological activity of BAD is highly controlled by phosphorylation. To further analyze the regulation of BAD function, the authors (Polzien L, Baljuls A, Albrecht M, Hekman M, Rapp UR) investigated the role of recently identified phosphorylation sites on BAD-mediated apoptosis.

    Publish: 2011/3/25

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