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  • Publish: 2014/9/16
  • Time: 3:57
Down syndrome, also known as trisomy 21, is a genetic disorder caused by the somatic aneuploidy of chromosome 21. It is typically associated with delayed physical growth, characteristic facial appearance, and mild to moderate intellectual disability. Down syndrome is the most common somatic aneuploidy in humans occurs in 1 out of 700 live births in all ethnic groups. Here we present a brief introduction to the common knowledge of Down syndrome.
TOP 10
  1. Western Blot
  2. Real-time PCR
  3. Reverse Transcription PCR
  4. Immunohistochemistry
  5. Indirect ELISA
  6. Polymerase Chain Reaction
  7. H&E Staining
  8. Cell Culture (Attached Cell)
  9. Immunofluorescence
  10. Competitive ELISA
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  • Northern Blot

    The northern blot is used to study gene expression by detection of RNA (or isolated mRNA). A general blotting procedure starts with the separation of RNA by electrophoresis. The RNA can then be transferred to a nylon membrane through a capillary system and detected with a hybridization probe.

    Publish: 2011/1/21

  • Nuclear and Cytoplasmic Protein Extraction

    Subcellular fractionation is extremely useful for assessing protein localization. This protocol shows how to separate and prepare of cytoplasmic and nuclear extracts from mammalian cultured cells.

    Publish: 2011/4/19

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