Support

  • Where to buy
  • Choose your location

AbVideo™ - The Ciliopathy-associated Protein Homologs RPGRIP1

Back to AbVideo™Video FAQ
  • Publish: 2011/8/30
  • Time: 8:00

by Abnova  


The aim of this study was to gain more insight in the function of two ciliopathy-associated protein homologs, RPGR interacting protein 1 (RPGRIP1), and RPGRIP1-like protein (RPGRIP1L). Base on the data, the authors hypothesize that RPGRIP1 and RPGRIP1L function as cilium-specific scaffolds that recruit a Nek4 signaling network which regulates cilium stability.


Related Video
   
  • BAD in Cancer Signalling

    BAD (Bcl-2 antagonist of cell death) belongs to the pro-apoptotic BH3-only subfamily of Bcl- 2 proteins. Physiological activity of BAD is highly controlled by phosphorylation. To further analyze the regulation of BAD function, the authors (Polzien L, Baljuls A, Albrecht M, Hekman M, Rapp UR) investigated the role of recently identified phosphorylation sites on BAD-mediated apoptosis.

    Publish: 2011/3/25

  • Chicken Antibody Extraction

    First identified in 1969, avian IgY has now become a well characterized research reagent commercially available. For decades, extensive research has been carried out on its biological function, physiochemical property, production and purification. More than a alternative to mammalian IgG, IgY possesses several advantages over polyclonal antibodies raised in mammals, such as a much more hygienic, cost efficient, and humane manufacturing process. Abnova now brings you our latest series of avian antibodies for your choice. Please visit the webpage "New Chicken Antibodies" for more information. Here we present a brief introduction to Chicken Antibody Extraction.

    Publish: 2014/7/29

  • Chicken Antibody Introduction

    First identified in 1969, avian IgY has now become a well characterized research reagent commercially available. For decades, extensive research has been carried out on its biological function, physiochemical property, production and purification. More than a alternative to mammalian IgG, IgY possesses several advantages over polyclonal antibodies raised in mammals, such as a much more hygienic, cost efficient, and humane manufacturing process. Abnova now brings you our latest series of avian antibodies for your choice. Please visit the webpage "New Chicken Antibodies" for more information. Here is a brief introduction for your first acquaintance of chicken antibody.

    Publish: 2014/7/1

  • Chicken Immune System

    First identified in 1969, avian IgY has now become a well characterized research reagent commercially available. For decades, extensive research has been carried out on its biological function, physiochemical property, production and purification. More than a alternative to mammalian IgG, IgY possesses several advantages over polyclonal antibodies raised in mammals, such as a much more hygienic, cost efficient, and humane manufacturing process. Abnova now brings you our latest series of avian antibodies for your choice. Please visit the webpage "New Chicken Antibodies" for more information. Here we present a brief introduction to the chicken immune system.

    Publish: 2014/7/15

  • Chicken Immunization

    First identified in 1969, avian IgY has now become a well characterized research reagent commercially available. For decades, extensive research has been carried out on its biological function, physiochemical property, production and purification. More than a alternative to mammalian IgG, IgY possesses several advantages over polyclonal antibodies raised in mammals, such as a much more hygienic, cost efficient, and humane manufacturing process. Abnova now brings you our latest series of avian antibodies for your choice. Please visit the webpage "New Chicken Antibodies" for more information. Here we present a brief introduction to the immunization of the chicken.

    Publish: 2014/7/22

  • Down Syndrome

    Down syndrome, also known as trisomy 21, is a genetic disorder caused by the somatic aneuploidy of chromosome 21. It is typically associated with delayed physical growth, characteristic facial appearance, and mild to moderate intellectual disability. Down syndrome is the most common somatic aneuploidy in humans occurs in 1 out of 700 live births in all ethnic groups. Here we present a brief introduction to the common knowledge of Down syndrome.

    Publish: 2014/9/16

  • Edwards Syndrome

    Edwards syndrome, also known as trisomy 18, is a genetic disorder resulted from the somatic aneuploidy with an extra chromosome 18. It is typically associated with significant infant mortality. Edwards syndrome is the second most common somatic aneuploidy after Down syndrome. Here we present a brief introduction to the common knowledge of Edwards syndrome.

    Publish: 2014/9/23

  • ELISA Substrate Kit - Introduction

    ELISA Substrate Kit is a series of extremely sensitive chemiluminescent substrate kit for detecting horseradish peroxidase (HRP) conjugates in ELISA. Its very intense signal output at 425 nm enables detection of low femtogram amounts of antigen. Here is a brief introduction to why you should choose our products for your ELISA assay.

    Publish: 2014/9/2

  • Fluorescence Dye - Protein Labeling

    As a novel product line, Abnova provides a complete selection of fluorescent labels covering the full working range of wavelengths, from 400nm to 850nm. The structures of our dyes are designed so as to provide great brightness and photo-stability, for high quality molecular imaging. As a more convenient and efficient way for fluorescent protein labeling, Abnova also provides our series of fluorescent dyes in kit format. Please visit the webpage "Fluorescent Dyes" for more information. Here is a brief introduction to why you should choose our products for your fluorescence labeling.

    Publish: 2014/8/12

  • Fluorescent Dye - Differential Gel Electrophoresis

    As a novel product line, Abnova provides a complete selection of fluorescent labels covering the full working range of wavelengths, from 400nm to 850nm. The structures of our dyes are designed so as to provide great brightness and photo-stability, for high quality molecular imaging. As an alternative application, 2D-PAGE electrophoresis represents a powerful and widely used method for the analysis of complex protein mixtures extracted from cells, tissues, or other biological samples. Abnova presents a series of DGE labeling kits for faster, easier and more accurate quantification in 2D-PAGE. Please visit the webpage "DGE Labeling Kit" for more information. Here is a brief introduction to why you should choose our products for your fluorescence labeling.

    Publish: 2014/8/19

  • Fluorescent Dye - Introduction

    As a novel product line, Abnova provides a complete selection of fluorescent labels covering the full working range of wavelengths, from 400nm to 850nm. The structures of our dyes are designed so as to provide great brightness and photo-stability, for high quality molecular imaging. Each fluorescent compound is available with many different reactive moieties, while retaining high photophysical features and different charge values (anionic, cationic, zwitterionic and neutral). Please visit the webpage "Fluorescent Dyes" for more information. Here we present a brief introduction to our fluorescence dye system.

    Publish: 2014/8/5

  • Klinefelter Syndrome

    Klinefelter syndrome, with the karyotype 47,XXY, is one of the commonest types of congenital chromosomal disorder in males. With an incidence of 0.1% to 0.2% of newborn male infants, it often causes hypogonadism and infertility. Although with different severity, most patients have normal lifespan as general public. Here we present a brief introduction to the common knowledge of Klinefelter syndrome.

    Publish: 2014/10/16

  • Patau Syndrome

    Patau Syndrome, resulted from chromosome 13 trisomy, is regarded the least common but the most severe among those somatic aneuploidies. It is typically associated with significant infant mortality. Clinical features of Patau syndrome include delayed development with central nervous system anomalies, midline facial defects, and urogenital malformations. Medical management of children with Trisomy 13 should be planned on a case-by-case basis according to the individual circumstances of the patient. Here we present a brief introduction to the common knowledge of Patau Syndrome.

    Publish: 2014/10/1

  • Prenatal Tests for Genetic Disorders

    To identify birth defects such as Down syndrome, chromosome abnormalities, and other genetic diseases, prenatal test is now widely accepted as a routine for pregnant women. Common tests including amniocentesis, ultrasonography, etc. can be basically divided into invasive or non-invasive methods according to the way of their appliance. An invasive method involves probes or needles being inserted into the uterus, and , on the contrary, non-invasive techniques adopt ultrasonography and maternal serum screens to gain the information of the fetus. Here we present a brief introduction to the most common kinds of prenatal tests along with some basic knowledge of genetic consultation.

    Publish: 2014/9/9

  • The Advantages of Chicken Antibody

    First identified in 1969, avian IgY has now become a well characterized research reagent commercially available. For decades, extensive research has been carried out on its biological function, physiochemical property, production and purification. More than a alternative to mammalian IgG, IgY possesses several advantages over polyclonal antibodies raised in mammals, such as a much more hygienic, cost efficient, and humane manufacturing process. Abnova now brings you our latest series of avian antibodies for your choice. Please visit the webpage "New Chicken Antibodies" for more information. Here we present a brief introduction to the advatages of chicken antibody.

    Publish: 2014/7/8

  • Trisomy X Syndrome

    Trisomy X Syndrome, resulted from sex chromosome X trisomy, is regarded the most common female aneuploidies. It is characterized with a broad spectrum of phenotypic variations. Although with different severity, most patients have normal lifespan as general public. Here we present a brief introduction to the common knowledge of Trisomy X Syndrome.

    Publish: 2014/10/9

  • Warsaw Breakage Syndrome

    Cohesinopathies are human developmental disorders caused by inherited defects in cellular components controlling the process of sister chromatid cohesion. This cohesion mechanism takes care of keeping the sister chromatids close together from the stage of DNA replication up until mitosis. Two syndromes were described so far in the group of cohesinopathes: Roberts syndrome and Cornelia de Lange syndrome. In Van der Lelij research, a third cohesinopathy is added to this group: The Warsaw Breakage syndrome, caused by mutations in DDX11/ChlR1.

    Publish: 2010/8/31

  • Western Blot Substrate Kit - Introduction

    ( http://www.abnova.com ) - WB substrate kit detection reagents are non-isotopic, luminol-based chemiluminescence substrate, designed for the chemiluminescent detection of immobilized proteins and immobilized nucleic acids conjugated with horseradish peroxidase (HRP). The peroxidase-catalyzed oxidation of luminol produces a weak flash of light at 425 nm. The incorporation of an electron transfer mediator into the buffer forces the flash signal into a glow and greatly improves the analytical characteristics of the reaction in terms of increased signal intensity and duration. Recent works have shown that, by addition of a suitable acylation catalyst, a further large increase in light output is observed. Here is a brief introduction to why you should choose our products for your fluorescence blotting. More videos at Abnova http://www.abnova.com

    Publish: 2014/8/26

  • XYY Syndrome

    XYY Syndrome is a sex chromosomal anueploidy caused by an Y chromosome in male individuals and thus resulted 47,XXY karyotype. In general XXY syndrome is regarded asymptomatic with certain cases reported to be at greater risk for behavioral problems, mild learning disability, delayed speech and language development, along with tall stature. Here we present a brief introduction to the common knowledge of XXY Syndrome.

    Publish: 2014/10/21

  • RSS
  • YouTube
  • Linkedin
  • Facebook