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AbVideo™ - BAD in Cancer Signalling

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  • Publish: 2011/3/25
  • Time: 6:08
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by Abnova  

BAD (Bcl-2 antagonist of cell death) belongs to the pro-apoptotic BH3-only subfamily of Bcl- 2 proteins. Physiological activity of BAD is highly controlled by phosphorylation. To further analyze the regulation of BAD function, the authors (Polzien L, Baljuls A, Albrecht M, Hekman M, Rapp UR) investigated the role of recently identified phosphorylation sites on BAD-mediated apoptosis.

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