Atomic force microscopy (AFM) is a very high-resolution type of scanning probe microscopy, with demonstrated resolution on the order of fractions of a nanometer, more than 1000 times better than the optical diffraction limit. The AFM is one of the foremost tools for imaging, measuring, and manipulating matter at the nanoscale. This video shows the AFM basic tutorial.
The Nexcelom Bioscience Cellometer® is a simple to use, automated cell counter designed to improve accuracy and repeatability. You just pipette 20μL of sample, insert the slide and click count. Cell Concentration, cell size and viability are displayed in less than 30 seconds.
With the aid of micromanipulator, precise physical interactions under microscopic level becomes achievable. In concert with hydraulic drive systems, it is principally the glass probe that makes the physical contack with target cell for purposes like single cell collection, injection, patch clamping, etc. Here is the presentation of a typical procedure for probe preparation, including steps of glass capillary pulling and micropipette tip processing. Instruments adopted here are MF-900 microforge and PC-10 puller, both from NARISHIGE Group.
With the aid of micromanipulator, precise physical interactions, like single cell collection, injection, patch clamping, etc. under microscopic level becomes achievable. In general, depending on the application, one or more micromanipulators can be docked on a microscope stage to operate in microscopes field of view. Here we present a typical procedure for single cell collection, including steps of cell aspiration and discharge. Instruments adopted here is MMO-203 Three-axis Oil Hydraulic Micromanipulator from NARISHIGE Group.
The Thermo Scientific Nanodrop® is a full-spectrum spectrophotometer that measures 1 ul samples with high accuracy and reproducibility. It utilizes a sample retention technology that eliminates the need for cumbersome cuvettes and allows for clean up in seconds.