CYCS polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CYCS.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human CYCS.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Identical to the related rat and mouse sequence.
Form
Lyophilized
Purification
Immunoaffinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL)
Immunohistochemistry (Frozen sections) (1 ug/mL)
Immunocytochemistry (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) staining of rat lung tissue with CYCS polyclonal antibody (Cat # PAB8027).Immunohistochemistry (Frozen sections)
Immunohistochemistry (Frozen sections) staining of rat lung tissue with CYCS polyclonal antibody (Cat # PAB8027).Immunocytochemistry
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Gene Info — CYCS
Entrez GeneID
54205Gene Name
CYCS
Gene Alias
CYC, HCS
Gene Description
cytochrome c, somatic
Omim ID
123970Gene Ontology
HyperlinkGene Summary
This gene encodes cytochrome c, a component of the electron transport chain in mitochondria. The heme group of cytochrome c accepts electrons from the b-c1 complex and transfers electrons to the cytochrome oxidase complex. Cytochrome c is also involved in initiation of apoptosis. Upon release of cytochrome c to the cytoplasm, the protein binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Many cytochrome c pseudogenes exist, scattered throughout the human genome. [provided by RefSeq
Other Designations
cytochrome c
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Interactome
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Pathway
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Disease
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Publication Reference
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Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.
Li K, Li Y, Shelton JM, Richardson JA, Spencer E, Chen ZJ, Wang X, Williams RS.
Cell 2000 May; 101(4):389.
Application:WB-Ce, Mouse, Embryonic Cell.
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Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.
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