TACR1 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
TACR1 polyclonal antibody (Cat # PAB7270) (1 ug/mL) staining of HeLa (1) and (0.5 ug/mL) Neuro2a (2) cell lysate (35 ug protein in RIPA buffer). Detected by chemiluminescence.
Immunofluorescence
TACR1 polyclonal antibody (Cat # PAB7270) Immunofluorescence analysis of paraformaldehyde fixed Neuro2a cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear and plasma membrane staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TACR1.
Immunogen
A synthetic peptide corresponding to human TACR1.
Sequence
C-EIPGDSSDRYHEQ
Host
Goat
Theoretical MW (kDa)
46.3, 35.7
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_001049.1 and NP_056542.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:28000)
Immunofluorescence (10 ug/mL)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TACR1 polyclonal antibody (Cat # PAB7270) (1 ug/mL) staining of HeLa (1) and (0.5 ug/mL) Neuro2a (2) cell lysate (35 ug protein in RIPA buffer). Detected by chemiluminescence.Immunofluorescence
TACR1 polyclonal antibody (Cat # PAB7270) Immunofluorescence analysis of paraformaldehyde fixed Neuro2a cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear and plasma membrane staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).Enzyme-linked Immunoabsorbent Assay
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Gene Info — TACR1
Entrez GeneID
6869Protein Accession#
NP_001049.1*;NP_056542.1*Gene Name
TACR1
Gene Alias
NK1R, NKIR, SPR, TAC1R
Gene Description
tachykinin receptor 1
Omim ID
162323Gene Ontology
HyperlinkGene Summary
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq
Other Designations
NK-1 receptor|neurokinin 1 receptor|tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor)|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
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Interactome
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Pathway
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Disease
- Alcoholism
- Anorexia Nervosa
- Asthma
- Bipolar Disorder
- Bulimia
- Chronic Disease
- Constipation
- Cough
- Endometriosis
+ View More Disease
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Publication Reference
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Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation.
Lai JP, Ho WZ, Kilpatrick LE, Wang X, Tuluc F, Korchak HM, Douglas SD.
PNAS 2006 May; 103(20):7771.
Application：IF, Human, THP-2 cells.
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Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation.
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