BMP5 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
The BMP5 polyclonal antibody (Cat # PAB3674) is used in Western blot to detect BMP5 in placenta tissue lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with BMP5 polyclonal antibody (Cat # PAB3674) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BMP5.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BMP5.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
The BMP5 polyclonal antibody (Cat # PAB3674) is used in Western blot to detect BMP5 in placenta tissue lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with BMP5 polyclonal antibody (Cat # PAB3674) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. -
Gene Info — BMP5
Entrez GeneID
653Protein Accession#
P22003Gene Name
BMP5
Gene Alias
MGC34244
Gene Description
bone morphogenetic protein 5
Omim ID
112265Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq
Other Designations
OTTHUMP00000016650
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Interactome
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Pathway
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Disease
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Publication Reference
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Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis.
Luo J, Dunn T, Ewing C, Sauvageot J, Chen Y, Trent J, Isaacs W.
Prostate 2002 May; 51(3):189.
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Transcriptional mRNA of BMP-2, 3, 4 and 5 in trigeminal nerve, benign and malignant peripheral nerve sheath tumors.
Jin Y, Lu HB, Liong E, Lau TY, Tipoe GL.
Histology and Histopathology 2001 Oct; 16(4):1013.
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Molecular cloning and characterization of human bone morphogenic protein (BMP)-5 gene promoter.
Sakaue M, Kitazawa S, Nishida K, Kitazawa R, Maeda S.
Biochemical and Biophysical Research Communications 1996 Apr; 221(3):768.
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Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis.
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