CCNC polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of CCNC polyclonal antibody (Cat # PAB3518) in HL-60 cell line lysates (35 ug/lane). CCNC (arrow) was detected using the purified polyclonal antibody (1:1000 dilution).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CCNC.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CCNC.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of CCNC polyclonal antibody (Cat # PAB3518) in HL-60 cell line lysates (35 ug/lane). CCNC (arrow) was detected using the purified polyclonal antibody (1:1000 dilution). -
Gene Info — CCNC
Entrez GeneID
892Protein Accession#
NP_005181;P24863Gene Name
CCNC
Gene Alias
CycC
Gene Description
cyclin C
Omim ID
123838Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016897
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Interactome
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Publication Reference
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Two isoforms of the human cyclin C gene are expressed differentially suggesting that they may have distinct functions.
Katona RL, Loyer P, Roby SK, Lahti JM.
Acta Biologica Hungarica 2007 Mar; 58(1):133.
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Highly frequent allelic loss of chromosome 6q16-23 in osteosarcoma: involvement of cyclin C in osteosarcoma.
Ohata N, Ito S, Yoshida A, Kunisada T, Numoto K, Jitsumori Y, Kanzaki H, Ozaki T, Shimizu K, Ouchida M.
International Journal of Molecular Medicine 2006 Dec; 18(6):1153.
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Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter.
Sinkkonen L, Malinen M, Saavalainen K, Vaisanen S, Carlberg C.
Nucleic Acids Research 2005 Apr; 33(8):2440.
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Two isoforms of the human cyclin C gene are expressed differentially suggesting that they may have distinct functions.
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