RNASEL polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: Human cell line RT-4, Lane 2: Human cell line U-251MG sp with RNASEL polyclonal antibody (Cat # PAB28675).
Immunohistochemistry
Immunohistochemical staining of human bronchus with RNASEL polyclonal antibody (Cat # PAB28675) shows cytoplasmic and membranous positivity in respiratory epithelial cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RNASEL.
Immunogen
Recombinant protein corresponding to amino acids of human RNASEL.
Sequence
HGAKEDFHPPAEDWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKIADTSEGGIYLGFYEKQEVAVKTFCEGSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLFVCVTLCEQTLEACLDVHRGEDVENEEDEFARNVLSSI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: Human cell line RT-4, Lane 2: Human cell line U-251MG sp with RNASEL polyclonal antibody (Cat # PAB28675).Immunohistochemistry
Immunohistochemical staining of human bronchus with RNASEL polyclonal antibody (Cat # PAB28675) shows cytoplasmic and membranous positivity in respiratory epithelial cells. -
Gene Info — RNASEL
Entrez GeneID
6041Gene Name
RNASEL
Gene Alias
DKFZp781D08126, MGC104972, MGC133329, PRCA1, RNS4
Gene Description
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
Gene Ontology
HyperlinkGene Summary
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq
Other Designations
2',5'-oligoisoadenylate synthetase-dependent|OTTHUMP00000033148|interferon-induced 2-5A-dependent RNase|ribonuclease 4|ribonuclease L
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Interactome
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Disease
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