CLDN1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of CLDN1 polyclonal antibody (Cat # PAB27031) in extracts from HeLa cells.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of CLDN1 polyclonal antibody (Cat # PAB27031) in paraffin-embedded human breast carcinoma tissue.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CLDN1.
Immunogen
A synthetic peptide corresponding to human CLDN1.
Host
Rabbit
Theoretical MW (kDa)
22
Reactivity
Human, Mouse, Rat
Specificity
CLDN1 polyclonal antibody detects endogenous levels of CLDN1 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of CLDN1 polyclonal antibody (Cat # PAB27031) in extracts from HeLa cells.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of CLDN1 polyclonal antibody (Cat # PAB27031) in paraffin-embedded human breast carcinoma tissue.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CLDN1
Entrez GeneID
9076Protein Accession#
O95832Gene Name
CLDN1
Gene Alias
CLD1, ILVASC, SEMP1
Gene Description
claudin 1
Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq
Other Designations
senescence-associated epithelial membrane protein 1
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Interactome
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Pathway
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Disease
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